SCHEMBL5541591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1921413	0.86	ALDH1A1 (0.57)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL5539830	0.86	AURKA (0.35)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL2592058	0.84	AURKA (0.59)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL1921298	0.81	ALDH1A1 (0.52)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL395435	0.80	ALDH1A1 (0.64)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL16481153	0.79	ACP1 (0.54)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL13462899	0.78	MAPT (0.55)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL10989377	0.78	STK10 (0.51)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL27962661	0.78	ALDH1A1 (0.48)	ALDH1A1TDP1POLBL3MBTL1AURKA
	SCHEMBL1921414	0.78	ALDH1A1 (0.61)	ALDH1A1TDP1POLBL3MBTL1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.