SCHEMBL5541877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL156897	0.68	POLB (0.47)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL17895476	0.65	ALDH1A1 (0.42)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL3607393	0.65	NOTUM (0.40)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL4540542	0.61	KDM4E (0.46)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL5536419	0.61	ALDH1A1 (0.37)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL160432	0.61	NOTUM (0.48)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL5545122	0.61	NOTUM (0.44)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL4463189	0.61	ADORA2A (0.41)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL5535789	0.61	NOTUM (0.40)	ALDH1A1KDM4ELMNAMEN1GAA
	SCHEMBL18331573	0.61	NOTUM (0.40)	ALDH1A1KDM4ELMNAMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.