Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 12/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 12/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.51 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.51 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541934 | 1.00 | CYP1A2 (0.60) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 | |
| SCHEMBL5542259 | 0.88 | CYP1A1 (0.54) | CYP1A2CYP1A1CYP1B1NFE2L2MAPT | |
| SCHEMBL5542266 | 0.88 | CYP1A1 (0.54) | CYP1A2CYP1A1CYP1B1NFE2L2MAPT | |
| SCHEMBL2090582 | 0.83 | CYP1A2 (0.66) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 | |
| SCHEMBL2090580 | 0.83 | CYP1A2 (0.66) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 | |
| SCHEMBL2094949 | 0.80 | CYP1A2 (0.66) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 | |
| SCHEMBL5537597 | 0.80 | NFE2L2 (0.51) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 | |
| SCHEMBL5537600 | 0.80 | NFE2L2 (0.51) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 | |
| SCHEMBL2094950 | 0.80 | CYP1A2 (0.66) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 | |
| SCHEMBL2092229 | 0.80 | CYP1A2 (0.70) | CYP1A2CYP1A1CYP1B1NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | CYP1A2 659/4885CYP1A1 1394/4885CYP1B1 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.