SCHEMBL5542015

SCHEMBL5542015

[CH2]CCCCCc1cccc(Oc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 8/20 0.51
CETP P11597 1/20 0.46
MGLL Q99685 1/20 0.46
FFAR1 O14842 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7653722 0.98 FDFT1 (0.52) FDFT1FFAR1FFAR4
SCHEMBL5545164 0.93 FDFT1 (0.51) FDFT1FFAR1FFAR4
SCHEMBL5540055 0.86 FFAR1 (0.50) FDFT1FFAR1FFAR4
SCHEMBL5539299 0.84 FFAR1 (0.51) FDFT1FFAR1FFAR4
SCHEMBL3028864 0.84 MGLL (0.50) MGLLFFAR1
SCHEMBL8862906 0.84 MGLL (0.50) MGLLFFAR1
SCHEMBL9026456 0.84 MGLL (0.50) MGLLFFAR1
SCHEMBL23085167 0.83 PPARA (0.62) CETP
SCHEMBL10922528 0.83 FDFT1 (0.54) FDFT1FFAR1
SCHEMBL10624215 0.83 PPARA (0.62) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476302-B2 α-ketoamide derivatives useful endothelial lipase inhibitors JANSSEN PHARMACEUTICA N.V. (BE) 2013-07-02 US claimed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
US-11981763-B2 Resin composition for stereolithographic modeling KURARAY NORITAKE DENTAL INC. (JP) 2024-05-14 US disclosed
EP-3900693-B1 USE OF A RESIN COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2024-03-20 EP disclosed
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom KURARAY CO., LTD. (JP) 2023-11-14 US disclosed
WO-2023127934-A1 ENERGY-RAY-CURABLE COMPOSITION FOR THREE-DIMENSIONAL SHAPING USE, DENTAL STRUCTURE, MOUTHPIECE, TEETH-STRAIGHTENING MOUTHPIECE, AND METHOD FOR PRODUCING DENTAL STRUCTURE クラレノリタケデンタル株式会社 2023-07-06 WO disclosed
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KURARAY NORITAKE DENTAL INC. (JP) 2023-07-06 US disclosed
WO-2023120611-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2023-06-29 WO disclosed
WO-2023120610-A1 DENTAL CURABLE COMPOSITION クラレノリタケデンタル株式会社 2023-06-29 WO disclosed
US-11655324-B2 Resin composition for optical shaping KURARAY NORITAKE DENTAL INC. (JP) 2023-05-23 US disclosed
CN-101172981-A 2,3-dihydroimidazo[2,1-b]oxazole compound OTSUKA PHARMA CO LTD (JP) 2008-05-07 CN disclosed
CN-100366624-C 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds OTSUKA PHARMA CO LTD (JP) 2008-02-06 CN disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
CN-1705670-A 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds OTSUKA PHARMA CO LTD (JP) 2005-12-07 CN disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
CN-1149214-C Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient ������������ʽ���� 2004-05-12 CN disclosed
US-6492364-B1 Triazolo and derivatives as chemokine inhibitors TORAY INDUSTRIES, INC. (JP) 2002-12-10 US disclosed
EP-1067130-A1 TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2001-01-10 EP disclosed
US-5670526-A ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom WASF2, COPE, ARCN1 FDFT1 924/4885CETP 3092/4885MGLL 2525/4885
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 FDFT1 852/4885CETP 4769/4885MGLL 4717/4885
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL FDFT1 3440/4885CETP 3271/4885MGLL 725/4885
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KIT, SETD7, SETDB1 FDFT1 3283/4885CETP 1037/4885MGLL 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.