Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.67 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388562 | 0.89 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL5503979 | 0.88 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL1537285 | 0.87 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL163444 | 0.87 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| Hydrochloric Acid SCHEMBL28331180 | 0.86 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL3435176 | 0.86 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL153062 | 0.86 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL1581156 | 0.84 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL3434038 | 0.84 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL9898388 | 0.84 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100564393-C | Separation of polypeptides containing racemized amino acids | NOVO NORDISK AS (DK) | 2009-12-02 | — | — | CN | claimed |
| CN-100503637-C | Glucagon-like peptide analog, its composition and its using method | ZHEJIANG BETA PHARMA INC (CN) | 2009-06-24 | — | — | CN | claimed |
| CN-100469791-C | Glucagon-like peptide-1 analogs | LILLY CO ELI (US) | 2009-03-18 | — | — | CN | claimed |
| CN-100374153-C | Use of GLP-1 or analogs in treatment of myocardial infraction | LILLY CO ELI (US) | 2008-03-12 | — | — | CN | claimed |
| CN-1839156-A | Separation of polypeptides containing racemized amino acids | NOVO NORDISK AS (DK) | 2006-09-27 | — | — | CN | claimed |
| CN-1832959-A | Polyethylene glycol linked GLP-1 compounds | LILLY CO ELI (US) | 2006-09-13 | — | — | CN | claimed |
| CN-1268391-C | Use of GLP-1 analogs and derivatives administered peripherally in regulation of obesity | LILLY CO ELI (US) | 2006-08-09 | — | — | CN | claimed |
| CN-1683408-A | Glucagon-like peptide analog, its composition and its using method | BEIDA MEDICINE DEV SHANGHAI CO (CN) | 2005-10-19 | — | — | CN | claimed |
| CN-1185257-C | Glucagon insulinotropic complexes, compositions and methods | LILLY CO ELI (US) | 2005-01-19 | — | — | CN | claimed |
| CN-1468258-A | Glucagon-like peptide-1 analogs | — | 2004-01-14 | — | — | CN | claimed |
| CN-1131674-A | Glucagon insulinotropic complexes, compositions and methods | LILLY CO ELI (US) | 1996-09-25 | — | — | CN | claimed |
| CN-103415300-A | N-terminal modified FGF21 compounds | NOVO NORDISK AS | 2013-11-27 | — | — | CN | disclosed |
| CN-101657443-B | [1,2,3] triazole-substituted quinolines and coumarins as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA LTD | 2013-10-23 | — | — | CN | disclosed |
| CN-102627638-A | Thiadiazole substituted coumarin derivatives and their use as leukotriene biosynthesis inhibitor | MERCK FROSST CANADA LTD | 2012-08-08 | — | — | CN | disclosed |
| CN-1756527-B | Regulation of mammalian hair growth | PROCTER & GAMBLE | 2010-12-08 | — | — | CN | disclosed |
| CN-1083052-A | Fluorine-containing hydroxyalkylquinolinacids acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1994-03-02 | — | — | CN | disclosed |
| CN-1061408-A | Saturated hydroxyalkyl quinolinic acids as leukotriene antagonists | MERCK FROSST CANADA INC (US) | 1992-05-27 | — | — | CN | disclosed |
| CN-1011196-B | Improved anti-inflammatory pharmaceutical compositions | PFIZER (US) | 1991-01-16 | — | — | CN | disclosed |
| CN-1047075-A | Luminandide medicine | MILLS RANDELL L (US) | 1990-11-21 | — | — | CN | disclosed |
| CN-85107521-A | The preparation method of improved formulation of antiinflammatory druge | — | 1986-08-06 | — | — | CN | disclosed |