Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 2/20 | 0.52 |
| ▸ | ME1 | P48163 | 2/20 | 0.52 |
| ▸ | ME3 | Q16798 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536209 | 0.89 | MAPT (0.81) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL15127501 | 0.89 | MAPT (0.79) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL5542804 | 0.87 | MAPT (0.77) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL5539971 | 0.87 | MAPT (0.76) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL11889801 | 0.86 | MAPT (0.74) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL2581059 | 0.86 | MAPT (0.75) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL5541814 | 0.86 | MAPT (0.74) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL27610366 | 0.85 | MAPT (0.74) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL5274074 | 0.85 | MAPT (0.74) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL5535580 | 0.84 | MAPT (0.72) | MAPTGAALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756751-A | Preparation method of 4- (4-hydroxyphenyl) -1-piperazine carboxylic acid ethyl ester | 宿迁晨阳医药科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-101665490-B | Method for preparing ketoconazole derivatives | EAST ASIA PHARMACEUTICAL CHEMICAL CO LTD | 2012-01-04 | — | — | CN | claimed |
| CN-101665490-A | Method for preparing ketoconazole derivatives | EAST ASIA PHARMACEUTICAL CHEMI | 2010-03-10 | — | — | CN | claimed |
| CN-117756751-B | Preparation method of 4- (4-hydroxyphenyl) -1-piperazine carboxylic acid ethyl ester | 宿迁晨阳医药科技有限公司 | 2025-07-15 | — | — | CN | disclosed |
| CN-117756751-B | Preparation method of 4- (4-hydroxyphenyl) -1-piperazine carboxylic acid ethyl ester | 宿迁晨阳医药科技有限公司 | 2025-07-15 | — | — | CN | disclosed |
| CN-117756751-A | Preparation method of 4- (4-hydroxyphenyl) -1-piperazine carboxylic acid ethyl ester | 宿迁晨阳医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117756751-A | Preparation method of 4- (4-hydroxyphenyl) -1-piperazine carboxylic acid ethyl ester | 宿迁晨阳医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117756751-A | Preparation method of 4- (4-hydroxyphenyl) -1-piperazine carboxylic acid ethyl ester | 宿迁晨阳医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| CN-101665490-A | Method for preparing ketoconazole derivatives | EAST ASIA PHARMACEUTICAL CHEMI | 2010-03-10 | — | — | CN | disclosed |
| CN-101665490-A | Method for preparing ketoconazole derivatives | EAST ASIA PHARMACEUTICAL CHEMI | 2010-03-10 | — | — | CN | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-4358449-A | 1-(1,3-Dioxolan-2-ylmethyl)-1H-1,2,4-triazoles and compositions | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-11-09 | — | — | US | disclosed |
| US-4335125-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-06-15 | — | — | US | disclosed |
| US-4223036-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-09-16 | — | — | US | disclosed |
| US-4144346-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | MAPT 4117/4885GAA 4165/4885LMNA 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.