Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | GAA | P10253 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665570 | 0.91 | MAPT (0.71) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL15127501 | 0.87 | MAPT (0.79) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1459682 | 0.86 | MAPT (0.57) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8557635 | 0.86 | MAPT (0.73) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5542804 | 0.85 | MAPT (0.77) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6160902 | 0.85 | MAPT (0.72) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5542809 | 0.85 | MAPT (1.00) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2581059 | 0.84 | MAPT (0.75) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9727540 | 0.84 | NPSR1 (0.68) | MAPTGAALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2569429 | 0.83 | MAPT (0.63) | MAPTGAALMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |