SCHEMBL554286

SCHEMBL554286

Oc1c(Cl)c(Cl)cc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.48
HPGD P15428 3/20 0.48
TSHR P16473 2/20 0.48
CASP1 P29466 1/20 0.48
CYP2A6 P11509 2/20 0.45
PTPN22 Q9Y2R2 1/20 0.45
TRPM4 Q8TD43 1/20 0.45
NQO2 P16083 1/20 0.43
CASP6 P55212 1/20 0.43
CYP1A2 P05177 1/20 0.43
NQO1 P15559 1/20 0.42
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
HTT P42858 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30499577 1.00 HSD17B10 (0.48) HSD17B10HPGDTSHRCASP1CYP2A6
Cyanate SCHEMBL7109909 0.91 HPGD (0.40) HSD17B10HPGDTSHRCASP1CYP2A6
SCHEMBL17329228 0.84 CASP6 (0.48) HSD17B10HPGDCYP2A6PTPN22TRPM4
SCHEMBL11293469 0.83 CYP2A6 (0.50) HSD17B10HPGDTSHRCYP2A6PTPN22
SCHEMBL23155051 0.81 POLB (0.45) HSD17B10HPGDCYP2A6PTPN22TRPM4
SCHEMBL1039782 0.79 CYP2A6 (0.56) HSD17B10TSHRCYP2A6TRPM4NQO2
SCHEMBL29629107 0.79 CYP2A6 (0.56) HSD17B10TSHRCYP2A6TRPM4NQO2
SCHEMBL8845560 0.79 PTPN22 (0.42) HSD17B10HPGDCYP2A6PTPN22TRPM4
SCHEMBL11298208 0.79 PTPN22 (0.42) HSD17B10HPGDCYP2A6PTPN22TRPM4
SCHEMBL6110249 0.79 TRPM4 (0.47) HSD17B10HPGDCYP2A6PTPN22TRPM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0448347-A2 Pigment composition NIPPON PAINT CO., LTD. (JP) 1991-09-25 EP claimed
US-4886760-A CHELATE COMPOUND SAVYON DIAGNOSTICS LIMITED (IL) 1989-12-12 US claimed
EP-0271713-A2 Method for preparing aqueous solutions containing chromogenic materials SAVYON DIAGNOSTICS LTD. (IL) 1988-06-22 EP claimed
EP-0196743-A2 Stable chemical compositions containing chromogenic materials and peroxides, and method for obtaining them SAVYON DIAGNOSTICS LTD. (IL) 1986-10-08 EP claimed
JP-62211561-A None JP disclosed
CN-116097093-A Preparation of Nucleated RBC (NRBC) analogs for use as reference blood controls in automated blood analyzers 生物辐射实验室股份有限公司 2023-05-09 CN disclosed
US-8318509-B2 Two-phase optical assays for analytes of no intrinsic opitcal contrast SAUNDERS PAUL ALEXANDER (US) 2012-11-27 US disclosed
US-20120034632-A1 TWO-PHASE OPTICAL ASSAYS FOR ANALYTES OF NO INTRINSIC OPITCAL CONTRAST SAUNDERS PAUL A (US) 2012-02-09 US disclosed
CN-100573327-C Underlayer coating forming composition containing dextrin ester compound NISSAN CHEMICAL IND LTD (JP) 2009-12-23 CN disclosed
CN-100547487-C The photoetching composition that forms antireflection film NISSAN CHEMICAL IND LTD (JP) 2009-10-07 CN disclosed
CN-101523292-A Method for manufacturing semiconductor device using quadruple-layer laminate NISSAN CHEMICAL IND LTD (JP) 2009-09-02 CN disclosed
CN-100535750-C Polyamide acid-containing composition for forming antireflective film NISSAN CHEMICAL IND LTD (JP) 2009-09-02 CN disclosed
US-3980659-A INSECTICIDES, INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3969302-A Process for the dyeing of colored shaped articles of high polymer, synthetic resins and preparations for such process CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 US disclosed
US-3937613-A DEVICE FOR THE DETERMINATION OF CHLORINE IN THE WATER OF SWIMMING POOLS ALPHA CHEMICALS (AUSTRALIA) PTY. LIMITED (AU) 1976-02-10 US disclosed
US-3932189-A Thermodevelopable photographic material containing high silver ion conducting substance FUJI PHOTO FILM CO., LTD. (JA) 1976-01-13 US disclosed