Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542975 | 0.86 | CXCR4 (0.36) | CXCR4HRH3 | |
| SCHEMBL5543312 | 0.86 | CXCR4 (0.36) | CXCR4HRH3 | |
| SCHEMBL27724414 | 0.84 | — | — | |
| SCHEMBL27672227 | 0.81 | LTA4H (0.40) | PARP1LTA4H | |
| Hydrochloric Acid SCHEMBL28130491 | 0.79 | LTA4H (0.39) | PARP1LTA4H | |
| Hydrochloric Acid SCHEMBL28861845 | 0.79 | LTA4H (0.39) | PARP1LTA4H | |
| SCHEMBL28101864 | 0.76 | — | — | |
| SCHEMBL27750679 | 0.76 | KMT2A (0.33) | LTA4HHRH3 | |
| SCHEMBL5539783 | 0.75 | CXCR4 (0.36) | PARP1CXCR4LTA4H | |
| SCHEMBL4836732 | 0.75 | CXCR4 (0.36) | PARP1CXCR4LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559983-B | Continuous hydrogenation method of pyrazine-2-ethyl formate and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2020-11-06 | — | — | CN | claimed |
| CN-111559983-A | Continuous hydrogenation method of pyrazine-2-ethyl formate and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-111559983-B | Continuous hydrogenation method of pyrazine-2-ethyl formate and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111559983-B | Continuous hydrogenation method of pyrazine-2-ethyl formate and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111559983-A | Continuous hydrogenation method of pyrazine-2-ethyl formate and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-111559983-A | Continuous hydrogenation method of pyrazine-2-ethyl formate and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-110317214-A | The huge ring of the diaryl of regulator as protein kinase | 特普医药公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110317213-A | The huge ring of the diaryl of regulator as protein kinase | 特普医药公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-106170289-B | Diaryl macrocycles as modulators of protein kinases | 特普医药公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-109923113-A | novel isoxazolyl ether derivatives as GABA A α 5 PAM | 豪夫迈·罗氏有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-106928245-B | A kind of Quinolizinone type compounds and its preparation method and application | 河南春风医药科技有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-1733725-A | Process for preparing 2-iminopyrrolidine derivatives | EISAI CO LTD (JP) | 2006-02-15 | — | — | CN | disclosed |
| CN-1720240-A | Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC-chemokine receptor ligands | SCHERING CORP (US) | 2006-01-11 | — | — | CN | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| CN-1516687-A | 3, 4-disubstituted cyclobutene-1, 2-diones as CXC-chemokine receptor ligands | ���鹫˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1503784-A | 2-iminopyrrolidine derivatives | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1130365-C | Alpha-1 adrenergic compounds, pharmaceutical compositions containing the same and uses thereof | ABBOTT CO (US) | 2003-12-10 | — | — | CN | disclosed |
| CN-1255498-A | Process for prepn. of growth hormone stimulating secretion agent and its intermediate | PFIZER PROD INC (US) | 2000-06-07 | — | — | CN | disclosed |
| CN-1246861-A | Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds | ABBOTT LAB (US) | 2000-03-08 | — | — | CN | disclosed |
| CN-87104648-A | Nitrofuran derivatives and preparation method thereof and the application in treatment | — | 1988-04-13 | — | — | CN | disclosed |