SCHEMBL554303

SCHEMBL554303

CO[Si](CCCC1=CC(=O)NC1=O)(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.31
PTGS2 P35354 4/20 0.31
GLS2 Q9UI32 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735941 0.81
SCHEMBL5703319 0.78 STAT3 (0.31)
SCHEMBL548121 0.78 STAT3 (0.35)
SCHEMBL5862353 0.77 DAO (0.38) ALOX5PTGS2GLS2
SCHEMBL549041 0.76 STAT3 (0.39) ALOX5PTGS2GLS2
SCHEMBL6910095 0.76 STAT3 (0.39) ALOX5PTGS2GLS2
SCHEMBL10428730 0.76 STAT3 (0.39) ALOX5PTGS2GLS2
SCHEMBL548131 0.76 STAT3 (0.39) ALOX5PTGS2GLS2
SCHEMBL10428620 0.76 STAT3 (0.39) ALOX5PTGS2GLS2
SCHEMBL549066 0.76 STAT3 (0.39) ALOX5PTGS2GLS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3074415-A1 NOVEL ULTRASHORT HYDROPHOBIC PEPTIDES THAT SELF-ASSEMBLE INTO NANOFIBROUS HYDROGELS AND THEIR USES Agency For Science, Technology And Research (SG) 2016-10-05 EP claimed
WO-2015080670-A1 NOVEL ULTRASHORT HYDROPHOBIC PEPTIDES THAT SELF-ASSEMBLE INTO NANOFIBROUS HYDROGELS AND THEIR USES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-06-04 WO claimed
US-20250163391-A1 NUCLEOTIDE TRANSIENT BINDING FOR SEQUENCING METHODS LIFE TECHNOLOGIES CORP (US) 2025-05-22 US disclosed
US-12152256-B2 Nucleotide transient binding for sequencing methods Life Technologies Corporation (US) 2024-11-26 US disclosed
US-20230193223-A1 NUCLEOTIDE TRANSIENT BINDING FOR SEQUENCING METHODS Life Technologies Corporation 2023-06-22 US disclosed
US-11447756-B2 Nucleotide transient binding for sequencing methods Life Technologies Corporation (US) 2022-09-20 US disclosed
US-11008612-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2021-05-18 US disclosed
CN-105189532-B Self-assembled ultrashort peptide hydrogels for wound healing, skin care and cosmetic applications 新加坡科技研究局 2020-11-03 CN disclosed
US-20200231948-A1 NUCLEOTIDE TRANSIENT BINDING FOR SEQUENCING METHODS Life Technologies Corporation 2020-07-23 US disclosed
US-10597642-B2 Nucleotide transient binding for sequencing methods Life Technologies Corporation (US) 2020-03-24 US disclosed
US-10293083-B2 Crosslinked peptide hydrogels AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-05-21 US disclosed
WO-2006118543-A1 NOVEL WATER-SOLUBLE NANOCRYSTALS COMPRISING A LOW MOLECULAR WEIGHT COATING REAGENT, AND METHODS OF PREPARING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-11-09 WO disclosed
US-7056471-B1 Ternary and quarternary nanocrystals, processes for their production and uses thereof AGENCY FOR SCIENCE TECHNOLOGY & RESEARCH (SG) 2006-06-06 US disclosed
US-20060110279-A1 TERNARY AND QUARTERNARY NANOCRYSTALS, PROCESSES FOR THEIR PRODUCTION AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-05-25 US disclosed
US-20050064604-A1 Assay based on doped nanoparticles BAYER TECHNOLOGY SERVICES GMBH 2005-03-24 US disclosed
WO-2004054923-A1 TERNARY AND QUATERNARY NANOCRYSTALS, PROCESSES FOR THEIR PRODUCTION AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2004-07-01 WO disclosed
US-6727065-B2 Methods of use of semiconductor nanocrystal probes for treating a material THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-27 US disclosed
EP-1166118-A1 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS The Regents of the University of California (US) 2002-01-02 EP disclosed
US-6207392-B1 COMPOUNDS CAPABLE OF LINKING TO ONE OR MORE RECEPTIVE MOLECULES; FOR THE DETECTION OF NUCLEOTIDE SEQUENCES; FOR THE RELEASE OF TOXIC COMPOUNDS IN TARGET CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-03-27 US disclosed
WO-2000055631-A1 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11008612-B2 Methods and apparatus for single molecule sequencing using energy transfer detection POLRMT, DNTT, POLM ALOX5 4289/4885PTGS2 3641/4885GLS2 681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.