Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13936213 | 0.83 | NR4A2 (0.69) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1092934 | 0.81 | NR4A2 (1.00) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31621504 | 0.81 | NR4A2 (1.00) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL15558170 | 0.80 | NR4A2 (0.69) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27873322 | 0.80 | NR4A2 (0.69) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1849453 | 0.80 | NR4A2 (0.69) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13209353 | 0.78 | NR4A2 (0.65) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1855462 | 0.78 | NR4A2 (1.00) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL2434968 | 0.78 | NR4A2 (0.65) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL15780214 | 0.78 | NR4A2 (0.65) | NR4A2KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122854-A1 | Carbocyclic Fused Cyclic Amines | BOEHRINGER MARKUS (CH) | 2012-05-17 | — | — | US | disclosed |
| US-20070112012-A1 | Carbocyclic fused cyclic amines | F. HOFFMANN-LA ROCHE AG (CH) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112012-A1 | Carbocyclic fused cyclic amines | F12, F11, F2 | NR4A2 3282/4885KMT2A 2480/4885MEN1 191/4885 |
| US-20120122854-A1 | Carbocyclic Fused Cyclic Amines | F12, F11, F2 | NR4A2 3282/4885KMT2A 2480/4885MEN1 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.