SCHEMBL5543367

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5542958	0.95	DRD2 (0.46)	DRD2DRD4HRH3KDM4EMAPT
	SCHEMBL5535606	0.94	DRD2 (0.45)	DRD2DRD4HRH3KDM4EMAPT
	SCHEMBL28845517	0.90	MAPT (0.46)	DRD2DRD4HRH3KDM4EMAPT
	SCHEMBL5536336	0.90	DRD2 (0.50)	DRD2DRD4HRH3KDM4EMAPT
	SCHEMBL5536527	0.87	SMN1; SMN2 (0.39)	DRD2DRD4HRH3MAPTALDH1A1
	SCHEMBL5547965	0.84	MAPT (0.43)	DRD2DRD4HRH3KDM4EMAPT
	SCHEMBL11524478	0.83	DRD2 (0.47)	DRD2DRD4HRH3KDM4EMAPT
	SCHEMBL5537248	0.82	DRD2 (0.53)	DRD2DRD4HRH3KDM4EMAPT
	SCHEMBL27610237	0.82	DRD2 (0.46)	DRD2DRD4KDM4EMAPTALDH1A1
	SCHEMBL5536950	0.82	SMN1; SMN2 (0.38)	DRD2DRD4HRH3ALOX15PARP11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.