SCHEMBL5543416

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL271200	1.00	HRH1 (0.52)	HRH1NAAALOXL2HRH4HRH3
	SCHEMBL5254429	0.98	HRH1 (0.48)	HRH1NAAALOXL2HRH4HRH3
	SCHEMBL5542341	0.93	HRH1 (0.46)	HRH1NAAALOXL2HRH4HRH3
	SCHEMBL1455815	0.85	LOXL2 (0.45)	HRH1NAAALOXL2HRH4HRH3
	SCHEMBL11102439	0.81	MAPT (0.48)	NAAALMNAMAPT
	SCHEMBL11103301	0.81	MAPT (0.48)	NAAALMNAMAPT
	SCHEMBL97331	0.81	MAPT (0.48)	NAAALMNAMAPT
	SCHEMBL11103088	0.81	MAPT (0.48)	NAAALMNAMAPT
	SCHEMBL11108660	0.81	MAPT (0.48)	NAAALMNAMAPT
	SCHEMBL96961	0.81	MAPT (0.48)	NAAALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.