SCHEMBL5543447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5539637	0.83	MAOB (0.50)	SLC9A1MAOBNOTUMTP53HPN
	SCHEMBL5536092	0.81	NPC1 (0.50)	SLC9A1MAOBNOTUMTP53
	SCHEMBL5539633	0.81	MAOB (0.48)	SLC9A1MAOBNOTUMTP53HPN
	SCHEMBL5543992	0.80	NPC1 (0.48)	NOTUMTP53KDM4EGUSBL3MBTL1
	SCHEMBL3758086	0.79	KDM4E (0.51)	SLC9A1KDM4EGAA
	SCHEMBL12163868	0.77	KDM4E (0.50)	SLC9A1MAOBHPNKDM4EKDM1A
	SCHEMBL4830084	0.77	KDM4E (0.50)	SLC9A1MAOBNOTUMHPNKDM4E
	SCHEMBL1805427	0.76	BRD4 (0.55)	SLC9A1NOTUMKDM4EKDM1APPARG
	SCHEMBL1805429	0.75	KDM1A (0.42)	KDM4EKDM1A
	SCHEMBL6509332	0.75	PPARG (0.52)	SLC9A1KDM4EKDM1APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.