Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3532628 | 0.90 | KDM1A (0.57) | PPARGPPARAKDM1AKDM4EALDH1A1 | |
| SCHEMBL5210139 | 0.88 | KDM1A (0.48) | PPARGPPARAKDM1AKDM4EALDH1A1 | |
| SCHEMBL1436917 | 0.86 | PPARA (0.54) | PPARGPPARAKDM1AKDM4EALDH1A1 | |
| SCHEMBL5204314 | 0.84 | KDM4E (0.54) | PPARGPPARAKDM1AKDM4EKDR | |
| SCHEMBL4888438 | 0.83 | PPARG (0.57) | PPARGPPARAKDM1AKDM4EMEN1 | |
| SCHEMBL12617314 | 0.83 | MAPT (0.53) | PPARGPPARAKDM1AKDM4E | |
| SCHEMBL12163868 | 0.83 | KDM4E (0.50) | PPARGPPARAKDM1AKDM4ESLC9A1 | |
| SCHEMBL4830084 | 0.83 | KDM4E (0.50) | PPARGPPARAKDM1AKDM4ESLC9A1 | |
| SCHEMBL1436051 | 0.82 | PPARA (0.51) | PPARGPPARAKDM4EALDH1A1HRH3 | |
| SCHEMBL979145 | 0.82 | KDM4E (0.65) | PPARGPPARAKDM4EKDRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1810795-A | Benzopyran compound and its prepn and use | SHANGHAI INST OF MEDICAMENTS C (CN) | 2006-08-02 | — | — | CN | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |
| WO-2005040099-A1 | PROCESSES FOR PRODUCING 3-SUBSTITUTED (2R,3R)-2-(PROTECTED AMINO)-3-HYDROXYPROPIONIC ACID DERIVATIVE AND INTERMEDIATE THEREFOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-06 | — | — | WO | disclosed |