SCHEMBL5543673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5541617	0.98	HDAC1 (0.51)	CYP1A2HDAC1HDAC8SIGMAR1HCAR2
	SCHEMBL5546625	0.98	HDAC1 (0.51)	CYP1A2HDAC1HDAC8SIGMAR1HCAR2
	SCHEMBL5544196	0.95	CYP1A2 (0.53)	CYP1A2HDAC1HDAC8SIGMAR1HCAR2
	SCHEMBL5535597	0.88	CYP1A2 (0.47)	CYP1A2HDAC1HDAC8SIGMAR1CYP2A6
	SCHEMBL19119318	0.83	KDM4E (0.44)	CYP1A2HDAC1HDAC8SIGMAR1CYSLTR1
	SCHEMBL30418669	0.80	SIGMAR1 (0.68)	CYP1A2HDAC1HDAC8SIGMAR1HCAR2
	SCHEMBL8957574	0.80	SIGMAR1 (0.54)	CYP1A2HDAC1HDAC8SIGMAR1HCAR2
	SCHEMBL2516	0.79	IDO1 (0.48)	HDAC1HDAC8SIGMAR1NAAAHDAC3
	SCHEMBL30418043	0.78	SIGMAR1 (0.66)	CYP1A2HDAC1HDAC8SIGMAR1HCAR2
	SCHEMBL2093292	0.78	SIGMAR1 (0.57)	CYP1A2HDAC1HDAC8SIGMAR1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.