Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27730466 | 0.98 | ALDH1A1 (0.42) | ALDH1A1USP2HPGDTDP1CYP3A4 | |
| SCHEMBL5547785 | 0.89 | ALDH1A1 (0.49) | ALDH1A1USP2HPGDTDP1CYP3A4 | |
| SCHEMBL5541768 | 0.87 | ALDH1A1 (0.51) | ALDH1A1USP2HPGDTDP1CYP3A4 | |
| SCHEMBL5539658 | 0.86 | ALDH1A1 (0.54) | ALDH1A1USP2HPGDTDP1CYP3A4 | |
| SCHEMBL5544234 | 0.86 | ALDH1A1 (0.54) | ALDH1A1USP2HPGDTDP1CYP3A4 | |
| SCHEMBL766361 | 0.80 | — | — | |
| SCHEMBL1532369 | 0.77 | ALDH1A1 (0.46) | ALDH1A1USP2HPGDTDP1CYP3A4 | |
| SCHEMBL983428 | 0.74 | — | — | |
| SCHEMBL12015523 | 0.74 | — | — | |
| SCHEMBL8146532 | 0.73 | ALDH1A1 (0.54) | ALDH1A1USP2HPGDTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749135-B | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2019-07-19 | — | — | CN | claimed |
| CN-106279082-B | Substituted furans chalcone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106905340-B | Benzofuran fluoro flavanone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106279082-A | Substituted furan chalcone derivant and preparation method thereof | 浙江大学 | 2017-01-04 | — | — | CN | claimed |
| CN-106243126-A | Substituted furan isoquinolines analog derivative and preparation method thereof | 浙江大学 | 2016-12-21 | — | — | CN | claimed |
| CN-106243121-A | Substituted furan-flavone alcohol derivatives and preparation method thereof | 浙江大学 | 2016-12-21 | — | — | CN | claimed |
| CN-101124229-A | Novel heterocyclic compounds for the treatment of inflammatory and allergic disorders | GLENMARK PHARMACEUTICALS SA (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-105899518-B | Fused ring compound and organic illuminating element containing it | 三星SDI株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-108884083-A | Benzo [ B ] furans as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-106456602-A | Substituted indole MCL-1 inhibitors | 范德比尔特大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-106336417-A | Substituted furan isoflavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | disclosed |
| CN-105899518-A | Fused-ring compound and organic light-emitting device comprising same | 三星SDI株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-105849112-A | Condensed cyclic compound and organic light emitting device including same | 三星SDI株式会社 | 2016-08-10 | — | — | CN | disclosed |
| EP-0114128-B1 | 3-AMINO-2-OXO-AZETIDINE DERIVATIVES CONTAINING IN POSITION 1 A NITROGEN HETEROCYCLIC RADICAL, PROCESS FOR THEIR PREPARATION, THEIR USE AS THERAPEUTICAL AGENTS AND INTERMEDIATES FOR THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1989-03-22 | — | — | EP | disclosed |
| EP-0214029-A1 | 1-Dethia-2-thia cephalosporanic-acid derivatives, process for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1987-03-11 | — | — | EP | disclosed |
| EP-0153229-A2 | 1-Dethia 2-thia-cephalosporanic acid derivatives, process and intermediates for their preparation, their use as therapeutic agents and the compositions containing them | ROUSSEL-UCLAF (FR) | 1985-08-28 | — | — | EP | disclosed |
| EP-0114128-A1 | 3-Amino-2-oxo-azetidine derivatives containing in position 1 a nitrogen heterocyclic radical, process for their preparation, their use as therapeutical agents and intermediates for their preparation | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | disclosed |
| EP-0104671-A2 | Oxime derivatives of 3-alkyloxy or 3-alkylthiomethyl-7-amino-thiazolylacetamido-cephalosporanic acid, their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1984-04-04 | — | — | EP | disclosed |
| EP-0076528-A2 | Oxime derivatives of 3-alkyloxy or 3-alkylthiomethyl 7-amino-thiazolylacetamido-cephalosporanic acid and their preparation | ROUSSEL-UCLAF (FR) | 1983-04-13 | — | — | EP | disclosed |
| EP-0034536-A2 | Oxime derivatives of 3-alkyloxy- or 3-alkylthiomethyl 7-amino-thiazolylacetamido cephalosporanic acid, their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1981-08-26 | — | — | EP | disclosed |