SCHEMBL5543912

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29804089	0.81	CA1 (0.43)	MAPTCA1CA2CA7CA9
	SCHEMBL23362956	0.81	CA1 (0.43)	MAPTCA1CA2CA7CA9
	SCHEMBL5543907	0.79	MAPT (0.37)	MAPTALDH1A1KDM4EL3MBTL1
	SCHEMBL2433995	0.78	PPOX (0.41)	MAPTALDH1A1KDM4EMAOB
	SCHEMBL6992092	0.78	MAPT (0.50)	MAPTALDH1A1KDM4EAKT1CA1
	SCHEMBL2472619	0.76	MAPT (0.57)	MAPTALDH1A1KDM4EAKT1IDO1
	SCHEMBL11248793	0.76	MAPT (0.53)	MAPTALDH1A1KDM4EAKT1CA1
	SCHEMBL9063898	0.76	MAPT (0.49)	MAPTALDH1A1KDM4EAKT1PTGS2
	SCHEMBL10712890	0.74	MAPT (0.54)	MAPTALDH1A1KDM4EAKT1CA1
	SCHEMBL506797	0.74	CA12 (0.36)	MAPTALDH1A1KDM4ECA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.