SCHEMBL5543970

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5535282	0.98	CTRC (0.35)	ALDH1A1USP2HPGDTDP1CTRC
	SCHEMBL5541566	0.93	CTRC (0.36)	ALDH1A1USP2HPGDTDP1CTRC
	SCHEMBL5541247	0.86	CTRC (0.38)	ALDH1A1HPGDCTRCDAOCHRM2
	SCHEMBL5547178	0.84	HDAC1 (0.33)	ALDH1A1USP2HPGDTDP1HDAC3
	SCHEMBL5535500	0.84	MAOB (0.32)	ALDH1A1USP2HPGDTDP1
	SCHEMBL5542602	0.83	MAOB (0.38)	ALDH1A1USP2HPGDTDP1
	SCHEMBL5540626	0.82	SIRT2 (0.32)	ALDH1A1HDAC3HDAC4HDAC1HDAC7
	SCHEMBL5545718	0.82	MAOB (0.33)	ALDH1A1HPGDDAOALOX15
	SCHEMBL5544415	0.81	MAOB (0.39)	ALDH1A1
	SCHEMBL27610378	0.81	MAPT (0.41)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.