SCHEMBL55443

SCHEMBL55443

CC(=O)c1ccccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.65
CES1 P23141 1/20 0.65
ALDH1A1 P00352 3/20 0.62
POLB P06746 2/20 0.58
HPGD P15428 3/20 0.51
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
SMO Q99835 1/20 0.48
KMT2A Q03164 1/20 0.48
JAK2 O60674 1/20 0.48
TYK2 P29597 1/20 0.48
MAPT P10636 1/20 0.48
ERCC5 P28715 1/20 0.48
FEN1 P39748 1/20 0.48
TSHR P16473 2/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17187884 1.00 CES2 (0.65) CES2CES1ALDH1A1POLBHPGD
SCHEMBL29875158 1.00 CES2 (0.65) CES2CES1ALDH1A1POLBHPGD
Methyl Alcohol SCHEMBL28944135 0.98 CES2 (0.62) CES2CES1ALDH1A1POLBHPGD
Water SCHEMBL7070088 0.98 CES2 (0.62) CES2CES1ALDH1A1POLBHPGD
Hydrochloric Acid SCHEMBL27995982 0.98 CES2 (0.62) CES2CES1ALDH1A1POLBHPGD
Trimethylammonium SCHEMBL27857033 0.93 CES2 (0.58) CES2CES1ALDH1A1POLBHPGD
SCHEMBL2153679 0.84 CES2 (0.48) CES2CES1ALDH1A1POLBHPGD
Ethyl Acetate SCHEMBL28944126 0.83 TSHR (0.52) CES2CES1ALDH1A1POLBHPGD
SCHEMBL1515824 0.82 CES2 (0.50) CES2CES1ALDH1A1POLBHPGD
SCHEMBL699212 0.81 TSHR (0.65) CES2CES1ALDH1A1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1615 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136801-A Preparation method of (R) -1- (2-chlorophenyl) -2- (tetrazole-2-yl) ethyl carbamate 浙江京新药业股份有限公司 2025-06-13 CN claimed
CN-115784987-B Compound related to pneumonia as well as preparation method and application thereof and pharmaceutical composition 国科温州研究院(温州生物材料与工程研究所) 2025-05-27 CN claimed
CN-119191952-A Ambacolat Process for the preparation of intermediates 合肥立方制药股份有限公司 2024-12-27 CN claimed
CN-118834123-A Method for preparing alpha-bromo-o-chloroacetophenone by utilizing microchannel reactor 江苏恩华药业股份有限公司 2024-10-25 CN claimed
CN-118184595-A Method for preparing key intermediate of cinnolamine ester 四川奥邦古得药业有限公司 2024-06-14 CN claimed
CN-115109759-B Carbonyl reductase LsCR mutant, engineering bacterium and application thereof in preparation of chiral alcohol by asymmetric reduction of carbonyl compound 浙江工业大学 2024-05-03 CN claimed
US-11958826-B1 6′-(2-chlorophenyl)-2′-ethoxy-3,4′-bipyridine-3′- carbonitrile as an antimicrobial compound King Faisal University (SA) 2024-04-16 US claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
CN-117025581-A Double-enzyme ordered immobilization method, product and application thereof 杭州师范大学 2023-11-10 CN claimed
CN-116082133-A Synthetic method of tulobuterol 上海医药工业研究院 2023-05-09 CN claimed
EP-1854160-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2007-11-14 EP claimed
WO-2006085319-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 2006-08-17 WO claimed
US-6833468-B2 Reacting an optically active imine with a compound that is a hemiacetal of a perfluoroalkylaldehyde or a hydrate of a perfluoroalkylaldehyde to obtain a condensate, hydrolyzing CENTRAL GLASS COMPANY, LIMITED (JP) 2004-12-21 US claimed
EP-1080072-B1 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES BAYER CROPSCIENCE AG (DE) 2004-08-04 EP claimed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP claimed
US-6489490-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-12-03 US claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-4417957-A CHLORINATED ACETOPHENONES; ACRYLIC ACID AND/OR METHACRYLIC ACID COLUMBIA CHEMICAL CORPORATION (US) 1983-11-29 US claimed
US-4024193-A Homogeneous hydrogenation process ICI UNITED STATES INC. (US) 1977-05-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958826-B1 6′-(2-chlorophenyl)-2′-ethoxy-3,4′-bipyridine-3′- carbonitrile as an antimicrobial compound CLSPN, PNN, MFN2 CES2 1159/4885CES1 4071/4885ALDH1A1 2689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.