Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.58 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.58 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.58 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.55 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.55 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2080380 | 0.81 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2080486 | 0.80 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4047547 | 0.78 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4055465 | 0.77 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3300823 | 0.75 | MAPK14 (0.80) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4055743 | 0.75 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3293561 | 0.74 | MAPK14 (0.75) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL27640941 | 0.74 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL12245421 | 0.74 | MAPK14 (0.88) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2079824 | 0.73 | MAPK14 (0.81) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |