⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832849 | 0.81 | S1PR4 (0.30) | — | |
| SCHEMBL29200088 | 0.76 | — | — | |
| SCHEMBL28051991 | 0.76 | ENPP2 (0.32) | — | |
| SCHEMBL5545454 | 0.76 | — | — | |
| SCHEMBL28101028 | 0.74 | — | — | |
| SCHEMBL28113642 | 0.74 | CYP3A4 (0.31) | — | |
| SCHEMBL5544646 | 0.74 | CYP3A4 (0.37) | — | |
| SCHEMBL27917779 | 0.73 | MEN1 (0.38) | — | |
| SCHEMBL28089149 | 0.70 | SRC (0.32) | — | |
| SCHEMBL27859177 | 0.69 | NPC1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429081-B | Process for preparing 4-amino-5-fluoro-3-halo-6- (substituted) pyridine-2-carboxylic acid esters | 陶氏益农公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-104093311-A | 6-amino-2-substituted-5-vinylsilylpyrimidine-4-carboxylic acid and esters and 4-amino-6-substituted-3-vinylsilylpyridine-2-carboxylic acid and esters as herbicides | DOW AGROSCIENCES LLC | 2014-10-08 | — | — | CN | disclosed |
| CN-103429081-A | Process for preparing 4-amino-5-fluoro-3-halo-6- (substituted) pyridine-2-carboxylic acid esters | DOW AGROSCIENCES LLC | 2013-12-04 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |