Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545483 | 0.95 | AOC3 (0.40) | AOC3MEN1KMT2ALIMK2 | |
| SCHEMBL4990208 | 0.94 | AOC3 (0.42) | AOC3PDK2PDK4 | |
| SCHEMBL5551582 | 0.93 | AOC3 (0.47) | AOC3MEN1KMT2ALIMK2 | |
| SCHEMBL5550205 | 0.92 | AOC3 (0.37) | AOC3 | |
| SCHEMBL4988537 | 0.91 | AOC3 (0.41) | AOC3 | |
| SCHEMBL4871878 | 0.89 | AOC3 (0.42) | AOC3 | |
| SCHEMBL5545451 | 0.88 | AOC3 (0.39) | AOC3 | |
| SCHEMBL4877774 | 0.86 | NPC1 (0.38) | AOC3 | |
| SCHEMBL4871240 | 0.85 | AOC3 (0.41) | AOC3 | |
| SCHEMBL4984740 | 0.85 | AOC3 (0.38) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | ASTELLAS PHARMA INC. (JP) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | VCAM1, VAPB, VAPA | AOC3 386/4885PDK2 3421/4885PDK4 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.