SCHEMBL5545795

SCHEMBL5545795

C1=CCC(c2ccccc2)C(c2ccccc2)=C1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.44
GOPC Q9HD26 1/20 0.44
TSHR P16473 2/20 0.30
KMT2A Q03164 2/20 0.30
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8525884 0.82 PTGS2 (0.44)
SCHEMBL20290918 0.75 AHR (0.39)
SCHEMBL8516623 0.75 CFTR (0.50) CFTRGOPCTSHRKMT2ADDB1
SCHEMBL13523395 0.74 SLC6A2 (0.36) TSHRKMT2AMEN1CYP3A4CYP2D6
SCHEMBL21416522 0.74 CFTR (0.34) CFTRGOPCTSHRKMT2ADDB1
SCHEMBL23096934 0.74 KDM1A (0.34) CFTRGOPCCYP3A4CYP2D6
SCHEMBL13645456 0.74 CYP19A1 (0.32) CFTRGOPCTSHRKMT2ADDB1
SCHEMBL15948339 0.74 CYP3A4 (0.41) CFTRGOPCKMT2AMEN1CYP3A4
SCHEMBL24633078 0.74 CFTR (0.31) CFTRGOPCCYP3A4
SCHEMBL9978052 0.74 CFTR (0.31) CFTRGOPCCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0209622-B1 HYDROTERPHENYLS MERCK PATENT GmbH (DE) 1989-06-07 EP claimed
EP-0094487-B1 HYDROTERPHENYLS, THEIR PREPARATION AND THEIR USE IN DIELECTRIC LIQUID CRYSTAL MATERIAL MERCK PATENT GmbH (DE) 1987-09-09 EP claimed
US-4620938-A Hydroterphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-04 US claimed
JP-6263691-A None JP disclosed
CN-113929635-B 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof 沈阳药科大学 2023-08-22 CN disclosed
US-7309145-B2 Light source apparatus and projection display apparatus SEIKO EPSON CORPORATION (JP) 2007-12-18 US disclosed
US-20050168990-A1 Light source apparatus and projection display apparatus SEIKO EPSON CORPORATION (JP) 2005-08-04 US disclosed
JP-H06263691-A HYDROTERPHENYL COMPOUND AND LIQUID CRYSTAL COMPOSITION MERCK PATENT GMBH 1994-09-20 JP disclosed
EP-0209622-A1 Hydroterphenyls MERCK PATENT GmbH (DE) 1987-01-28 EP disclosed
US-4620938-A Hydroterphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-04 US disclosed
US-4620938-A Hydroterphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-04 US disclosed
US-4620938-A Hydroterphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-04 US disclosed
EP-0094487-A1 Hydroterphenyls, their preparation and their use in dielectric liquid crystal material MERCK PATENT GmbH (DE) 1983-11-23 EP disclosed
EP-0012579-A2 Pressure-sensitive mark-recording systems and solutions for use in such systems MONSANTO EUROPE S.A./N.V. (BE) 1980-06-25 EP disclosed
US-3966624-A LUBRICANTS SUN OIL COMPANY OF PENNSYLVANIA (US) 1976-06-29 US disclosed