Styrene

Styrene

SCHEMBL5546418

C=C(C)C(=O)O.C=CC(=O)OCCCC.C=Cc1ccccc1.[NaH]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.56
HPGD P15428 1/20 0.56
THRB P10828 3/20 0.46
TDP1 Q9NUW8 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 3/20 0.41
ATM Q13315 1/20 0.41
HCAR2 Q8TDS4 1/20 0.40
THRA P10827 1/20 0.40
APP P05067 1/20 0.40
MAPK1 P28482 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1563744 0.99 TSHR (0.58) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3915927 0.96 TSHR (0.55) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL15770166 0.95 TSHR (0.54) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL29157680 0.95 TSHR (0.54) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL7116743 0.94 TSHR (0.52) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL7903211 0.94 TSHR (0.52) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL195506 0.94 TSHR (0.52) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL8097086 0.94 TSHR (0.51) TSHRHPGDTHRBALDH1A1CYP3A4
Styrene SCHEMBL28616597 0.92 TSHR (0.59) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL4798421 0.92 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1441259-B1 Toner and developer for developing latent electrostatic images, and image forming apparatus RICOH KK (JP) 2007-07-25 EP disclosed
US-7129013-B2 Toner and developer for developing latent electrostatic images, and image forming apparatus RICOH COMPANY, LTD. (JP) 2006-10-31 US disclosed
US-20040209181-A1 Toner and developer for developing latent electrostatic images, and image forming apparatus RICOH COMPANY, LTD. (JP) 2004-10-21 US disclosed
EP-1441259-A1 Toner and developer for developing latent electrostatic images, and image forming apparatus Ricoh Company (JP) 2004-07-28 EP disclosed