SCHEMBL5547251

SCHEMBL5547251

Cc1cc(C)c(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.58
CYP2A6 P11509 2/20 0.50
CYP2B6 P20813 1/20 0.50
BACE1 P56817 1/20 0.48
DHFR P00374 1/20 0.47
ALDH1A1 P00352 4/20 0.42
AKT1 P31749 1/20 0.41
AKT2 P31751 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PSMB5 P28074 1/20 0.41
ALOX5 P09917 1/20 0.41
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
BCL2L1 Q07817 1/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
TSHR P16473 1/20 0.40
ACHE P22303 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4830408 0.92 ESR2 (0.60) ESR2CYP2A6CYP2B6BACE1DHFR
SCHEMBL16186712 0.84 ESR2 (0.48) ESR2CYP2A6CYP2B6BACE1DHFR
SCHEMBL20779245 0.84 ESR2 (0.48) ESR2CYP2A6CYP2B6BACE1DHFR
SCHEMBL15856366 0.84 ESR2 (0.48) ESR2CYP2A6CYP2B6BACE1DHFR
SCHEMBL6880149 0.84 BACE1 (0.62) ESR2CYP2A6CYP2B6BACE1DHFR
SCHEMBL13502108 0.82 ESR2 (0.47) ESR2CYP2A6CYP2B6BACE1DHFR
SCHEMBL26050424 0.82 LDHA (0.47) ESR2CYP2A6CYP2B6DHFRALDH1A1
SCHEMBL5952446 0.80 PDE4A (0.52) ESR2CYP2A6CYP2B6BACE1DHFR
SCHEMBL26346234 0.80 BACE1 (0.65) ESR2CYP2A6CYP2B6BACE1DHFR
Ammonia Solution, Strong SCHEMBL27938002 0.80 ESR2 (0.50) ESR2CYP2A6CYP2B6BACE1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7295802-B2 Image forming apparatus using a cleaning unit for preventing noises RICOH COMPANY, LTD (JP) 2007-11-13 US disclosed
US-20070110488-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDE THEREFOR KABATA TOSHIYUKI 2007-05-17 US disclosed
US-7181156-B2 Image forming apparatus using a cleaning member for preventing noises and process cartridge therefor RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-20050069357-A1 Image forming apparatus and process cartridge therefor RICOH COMPANY, LTD (JP) 2005-03-31 US disclosed
US-5561016-A HAVING PHOTOCONDUCTIVE LAYER CONTAINING CHARGE GENERATING MATERIAL, POLYVINYL BUTYRAL BINDER, CHARGE TRANSPORTING MATERIAL AND BIPHENYL(OR DERIVATIVE) ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 1996-10-01 US disclosed
US-4331439-A Process for preventing color migration in colored moldings of polyoxymethylene resins ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-05-25 US disclosed