Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.51 |
| ▸ | PDE4A | P27815 | 14/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016490 | 0.85 | PDE4D (0.63) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL5016527 | 0.82 | ALDH1A1 (0.53) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL5018084 | 0.81 | NPC1 (0.62) | — | |
| SCHEMBL6494769 | 0.75 | PDE4D (0.55) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5023369 | 0.75 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4028281 | 0.73 | PDE4D (0.63) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL5023283 | 0.73 | PDE4D (0.63) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4026196 | 0.72 | PDE4D (0.64) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL15270505 | 0.71 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL5016448 | 0.71 | PDE4D (0.61) | PDE4DPDE4BPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554262-B1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD (IN) | 2007-12-05 | — | — | EP | claimed |