Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537936 | 0.86 | KCNH2 (0.47) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5537159 | 0.86 | PTGS1 (0.49) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5537931 | 0.86 | KCNH2 (0.47) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5537165 | 0.86 | PTGS1 (0.49) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5543725 | 0.84 | KCNH2 (0.50) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5543720 | 0.84 | KCNH2 (0.50) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5535213 | 0.82 | PTGS1 (0.63) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5535209 | 0.82 | PTGS1 (0.63) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5542567 | 0.82 | PTGS1 (0.63) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C | |
| SCHEMBL5541677 | 0.82 | SIGMAR1 (0.47) | PTGS1SLC6A2SLC6A4KCNH2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |