Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580418 | 0.72 | KDM4E (0.51) | BRD4CA12BRPF1CA9KAT2B | |
| SCHEMBL6390410 | 0.72 | KDM4E (0.51) | BRD4CA12BRPF1CA9KAT2B | |
| SCHEMBL3282756 | 0.71 | MAPT (0.39) | BRD4CA12BRPF1CA9KAT2B | |
| SCHEMBL7014694 | 0.70 | KDM4E (0.42) | KDM4ECYP1A2TSHRCYP2C19MEN1 | |
| SCHEMBL1451027 | 0.70 | BRPF1 (0.50) | BRD4CA12BRPF1CA9KAT2B | |
| SCHEMBL1823973 | 0.69 | GRM5 (0.34) | KDM4ENQO2TSHRALDH1A1HSD17B10 | |
| SCHEMBL2013280 | 0.69 | CLK4 (0.41) | KDM4ECYP1A2ALDH1A1HSD17B10CLK4 | |
| SCHEMBL5995444 | 0.69 | KDM4E (0.53) | BRD4CA12BRPF1CA9KAT2B | |
| SCHEMBL28584436 | 0.68 | KDM4E (0.43) | BRD4CA12BRPF1CA9KAT2B | |
| SCHEMBL30049664 | 0.68 | FGFR1 (0.40) | BRD4CA12BRPF1CA9KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1780211-A2 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1775295-A1 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-04-18 | — | — | EP | disclosed |