Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 19/20 | 0.45 |
| ▸ | LYN | P07948 | 18/20 | 0.45 |
| ▸ | SRC | P12931 | 18/20 | 0.45 |
| ▸ | KDR | P35968 | 18/20 | 0.45 |
| ▸ | HCK | P08631 | 16/20 | 0.45 |
| ▸ | INSR | P06213 | 16/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825136 | 0.90 | LCK (0.55) | LCKLYNSRCKDRHCK | |
| SCHEMBL13301928 | 0.82 | LCK (0.47) | LCKLYNSRCKDRHCK | |
| SCHEMBL3241898 | 0.81 | KDR (0.55) | LCKLYNSRCKDRHCK | |
| SCHEMBL13301782 | 0.80 | LCK (0.47) | LCKLYNSRCKDRHCK | |
| SCHEMBL13301827 | 0.80 | LCK (0.45) | LCKLYNSRCKDRHCK | |
| SCHEMBL13301994 | 0.80 | HCK (0.44) | LCKLYNSRCKDRHCK | |
| SCHEMBL13301821 | 0.79 | LCK (0.45) | LCKLYNSRCKDRHCK | |
| SCHEMBL1827988 | 0.79 | LCK (0.58) | LCKLYNSRCKDRHCK | |
| SCHEMBL13301855 | 0.79 | LCK (0.45) | LCKLYNSRCKDRHCK | |
| SCHEMBL1824307 | 0.79 | LCK (0.59) | LCKLYNSRCKDRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758892-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123719-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2005-12-29 | — | — | WO | disclosed |