Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 16/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056838 | 0.93 | IMPDH2 (0.46) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6533062 | 0.90 | IMPDH2 (0.45) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6531402 | 0.90 | IMPDH2 (0.46) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5056202 | 0.89 | IMPDH2 (0.46) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL16508273 | 0.88 | IMPDH2 (0.44) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5134743 | 0.88 | IMPDH2 (0.44) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL14877035 | 0.88 | IMPDH2 (0.46) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5148499 | 0.87 | IMPDH2 (0.45) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL16508284 | 0.87 | IMPDH2 (0.44) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5053656 | 0.86 | IMPDH2 (0.44) | IMPDH2AAK1IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765336-A2 | ANGIOGENESIS INHIBITORS | THE JOHNS-HOPKINS UNIVERSITY (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006004795-A2 | ANGIOGENESIS INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-01-12 | — | — | WO | disclosed |