SCHEMBL554810

SCHEMBL554810

Nc1ccc(Oc2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.61
MAOB P27338 1/20 0.61
PDE7A Q13946 2/20 0.59
MAPT P10636 4/20 0.59
CYP2C9 P11712 3/20 0.59
HPGD P15428 3/20 0.59
ALDH1A1 P00352 3/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
KDM4E B2RXH2 1/20 0.59
MEN1 O00255 1/20 0.59
CYP2D6 P10635 1/20 0.59
KMT2A Q03164 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CYP3A4 P08684 2/20 0.53
FFAR1 O14842 2/20 0.53
LMNA P02545 2/20 0.52
TTR P02766 2/20 0.52
NR1I2 O75469 1/20 0.52
PGR P06401 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29553590 0.89 MAOA (0.61) MAOAMAOBPDE7AMAPTCYP2C9
SCHEMBL554722 0.89 MAOA (0.61) MAOAMAOBPDE7AMAPTCYP2C9
SCHEMBL4318630 0.88 PDE7A (0.63) MAOAMAOBPDE7AMAPTCYP2C9
SCHEMBL3438989 0.88 MAPT (0.62) MAPTCYP2C9HPGDALDH1A1CYP1A2
SCHEMBL8904604 0.85 PDE7A (0.59) MAOAMAOBPDE7AMAPTCYP2C9
SCHEMBL9630149 0.85 MAOA (0.61) MAOAMAOBPDE7AMAPTCYP2C9
SCHEMBL4962861 0.84 TTR (0.60) MAPTCYP2C9HPGDALDH1A1MEN1
Hydrochloric Acid SCHEMBL11339581 0.82 TTR (0.58) MAPTCYP2C9HPGDALDH1A1CYP1A2
SCHEMBL21620367 0.81 FFAR1 (0.65) MAPTCYP2C9HPGDALDH1A1CYP1A2
SCHEMBL20565912 0.81 MAOA (0.57) MAOAMAOBPDE7AMAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7206800-A None JP disclosed
EP-3797991-B1 PREPREG AND PRODUCTION METHOD THEREFOR, SLIT TAPE PREPREG, CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-10-29 EP disclosed
US-12448510-B2 Prepreg, method for producing same, and slit tape prepreg TORAY INDUSTRIES, INC. (JP) 2025-10-21 US disclosed
EP-3995536-B1 PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-06-18 EP disclosed
CN-119707816-A Pyrazole hydrazide derivative containing diphenyl ether unit as well as preparation method and application thereof 江苏海洋大学 2025-03-28 CN disclosed
US-20250051335-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2025-02-13 US disclosed
CN-118852135-A N-acyl sulfonamide compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-10-29 CN disclosed
US-20240166798-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2024-05-23 US disclosed
EP-4368182-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS Consejo Superior De Investigaciones Científicas - CSIC (ES) 2024-05-15 EP disclosed
EP-4314108-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2024-02-07 EP disclosed
JP-H07206800-A PHENYLHYDRAZINE DERIVATIVE HODOGAYA CHEM CO LTD 1995-08-08 JP disclosed
EP-0355049-A2 Heterocyclic compounds ZENECA LIMITED (GB) 1990-02-21 EP disclosed
US-4391995-A 4-Phenoxy-phenoxy-alkane-carboxylic acid derivatives and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
EP-0034723-B1 METHOD FOR THE PREPARATION OF 4-PHENOXY PHENOLS HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-18 EP disclosed
US-4355189-A Process for the preparation of 4-phenoxyphenols HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed
US-4316993-A Process for the preparation of 4-phenoxy-phenols HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-23 US disclosed
US-4301295-A ANTILIPEMIC AND ANTICHOLESTEROL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-17 US disclosed
EP-0034723-A2 Method for the preparation of 4-phenoxy phenols HOECHST AKTIENGESELLSCHAFT (DE) 1981-09-02 EP disclosed
US-4238626-A ANTICHOLESTEROL AND ANTILIPEMIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-09 US disclosed
US-4056553-A INTERMEDIATES FOR MONOAZO DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051335-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS TTBK1, TTBK2, MAPT MAOA 1189/4885MAOB 387/4885PDE7A 4556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.