SCHEMBL5548258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2095293	0.80	PTGS1 (0.50)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL2095294	0.80	PTGS1 (0.50)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL2090789	0.78	CYP1A2 (0.53)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL2094532	0.78	CYP1A2 (0.53)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL28469501	0.78	CYP1A2 (0.54)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL5546301	0.78	CYP1A2 (0.46)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL5546304	0.78	CYP1A2 (0.46)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL11443780	0.77	CYP1A2 (0.55)	CYP1A2PTGS1FBP1CA1CA2
	SCHEMBL28469503	0.77	CYP1A2 (0.53)	CYP1A2PTGS1CA1CA2HDAC3
	SCHEMBL9773322	0.77	HSD17B10 (0.45)	CYP1A2FBP1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.