Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Amylene Hydrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amylene Hydrate SCHEMBL9631192 | 0.91 | — | — | |
| Amylene Hydrate SCHEMBL2013421 | 0.91 | ALDH1A1 (0.54) | — | |
| Amylene Hydrate SCHEMBL10721 | 0.91 | — | — | |
| Amylene Hydrate SCHEMBL9619268 | 0.87 | — | — | |
| Amylene Hydrate SCHEMBL9644533 | 0.87 | — | — | |
| Amylene Hydrate SCHEMBL7624044 | 0.87 | — | — | |
| Amylene Hydrate SCHEMBL7632117 | 0.87 | — | — | |
| Amylene Hydrate SCHEMBL11225654 | 0.87 | — | — | |
| Amylene Hydrate SCHEMBL22233971 | 0.87 | — | — | |
| Amylene Hydrate SCHEMBL9619592 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646426-B1 | Process for the preparation of nebivolol | MENARINI INT OPERATIONS LU SA (LU) | 2015-10-07 | — | — | EP | claimed |
| EP-1114042-B1 | PROCESS FOR PREPARING 3-ISOCHROMANONE | SYNGENTA LTD (GB) | 2007-12-12 | — | — | EP | claimed |
| EP-0008686-A2 | Synthesis of phenyl-propyl morpholine and piperidine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-03-19 | — | — | EP | claimed |
| CN-114384169-B | Method for rapidly analyzing volatile flavor substances in white spirit based on large-volume sample injection static headspace gas chromatograph-mass spectrometer | 贵州茅台酒股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-107428748-A | The method that halogenation azaindole compounds are prepared using PYBROP | VIIV保健英国第四有限公司 | 2017-12-01 | — | — | CN | disclosed |
| WO-2012093411-A2 | PROCESS FOR THE PREPARATION OF R-(-)-3- (CARBAMOYLMETHYL)-5-METHYLHEXANOIC ACID AND THE INTERMEDIATES | DR BRAJA SUNDAR PRADHAN (IN) | 2012-07-12 | — | — | WO | disclosed |
| US-4609713-A | Phenothiazinium perhalide crosslinking agent for polymer containing plurality of secondary amine moieties. | THE DOW CHEMICAL COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| EP-0043521-B1 | PROCESS FOR THE PREPARATION OF PINACOLONE | BAYER AG (DE) | 1984-05-16 | — | — | EP | disclosed |