Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4533199 | 1.00 | MEN1 (0.42) | MEN1GAAKMT2AGRIK1SLC7A5 | |
| SCHEMBL11016322 | 0.83 | SLC1A1 (0.44) | MEN1GAAKMT2AGRIK1APLNR | |
| SCHEMBL2580333 | 0.83 | SLC1A1 (0.44) | MEN1GAAKMT2AGRIK1APLNR | |
| SCHEMBL4954829 | 0.83 | SLC1A1 (0.44) | MEN1GAAKMT2AGRIK1APLNR | |
| SCHEMBL21689957 | 0.78 | GRIK1 (0.40) | MEN1GAAKMT2AGRIK1SLC7A5 | |
| SCHEMBL9845867 | 0.77 | MEN1 (0.47) | MEN1GAAKMT2AGRIK1SLC7A5 | |
| SCHEMBL14904434 | 0.77 | CYP2D6 (0.46) | MEN1GAAKMT2AAPLNRCA1 | |
| SCHEMBL38112 | 0.76 | GRIK1 (0.47) | GRIK1SLC7A5GRIK2SLC1A1SLC1A3 | |
| SCHEMBL2024581 | 0.76 | GRIK1 (0.47) | GRIK1SLC7A5GRIK2SLC1A1SLC1A3 | |
| SCHEMBL38111 | 0.76 | GRIK1 (0.47) | GRIK1SLC7A5GRIK2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556358-B1 | ENANTIOSELECTIVE ALKYLATION OF TRICYCLIC COMPOUNDS | SCHERING CORP (US) | 2007-06-20 | — | — | EP | claimed |