Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900748 | 0.74 | PLD1 (0.42) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL6627980 | 0.74 | CCNA2 (0.31) | — | |
| SCHEMBL12900583 | 0.72 | DDB1 (0.39) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL12900585 | 0.72 | HTR2C (0.33) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL5314288 | 0.71 | CYP2D6 (0.33) | SYKAURKB | |
| SCHEMBL30983619 | 0.71 | HRH3 (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL5259101 | 0.70 | HRH4 (0.31) | — | |
| SCHEMBL22566872 | 0.69 | HTR2C (0.34) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL5345232 | 0.69 | HTR2C (0.33) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27502044 | 0.69 | ADRA1A (0.36) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |