Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 4/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2082596 | 0.83 | NTRK1 (0.47) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2084854 | 0.80 | CDC25B (0.43) | MAPK14KDM4EMAPK1TDP1L3MBTL1 | |
| SCHEMBL2082645 | 0.74 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2082620 | 0.73 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2084403 | 0.71 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083268 | 0.71 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2082474 | 0.71 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083671 | 0.71 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL17244248 | 0.71 | L3MBTL1 (0.36) | MAPK14KDM4EL3MBTL1CDC25BCDK8 | |
| SCHEMBL2083538 | 0.70 | HPGD (0.47) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |