Sugi Predict

Sugi Predict / Compounds / SCHEMBL554883

SCHEMBL554883

SCHEMBL554883

CCCCCCCCCCCCCCCCCOCCC

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.64
▸ THRB P10828 2/20 0.64
▸ MEN1 O00255 1/20 0.64
▸ KMT2A Q03164 1/20 0.64
▸ MAPT P10636 1/20 0.64
▸ USP2 O75604 1/20 0.54
▸ CES2 O00748 2/20 0.52
▸ TSHR P16473 2/20 0.50
▸ ALDH1A1 P00352 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ CES1 P23141 1/20 0.46
▸ LPAR5 Q9H1C0 1/20 0.44
▸ LPAR1 Q92633 2/20 0.42
▸ LPAR3 Q9UBY5 2/20 0.42
▸ LPAR2 Q9HBW0 1/20 0.42
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505160 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL87529 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL4486361 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL17713591 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL19541813 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL21044619 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL200908 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL2153214 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL777304 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT
SCHEMBL1931398 1.00 HTT (0.64) HTTTHRBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110373272-B Additive for removing plant wax and pretreatment method of plant raw material 中国烟草总公司郑州烟草研究院 2022-09-09 — — CN claimed
US-20120032122-A1 METHOD FOR FORMING A CADMIUM CONTAINING NANOCRYSTAL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-02-09 — — US claimed
WO-2009020430-A2 METHOD OF FORMING A CADMIUM CONTAINING NANOCRYSTAL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-02-12 — — WO claimed
US-20230287029-A1 ANTIVIRAL PRODRUGS, PHARMACEUTICAL FORMULATIONS, AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-09-14 — — US disclosed
CN-110373272-B Additive for removing plant wax and pretreatment method of plant raw material 中国烟草总公司郑州烟草研究院 2022-09-09 — — CN disclosed
US-20170253628-A1 PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL TRUSTEE 2017-09-07 — — US disclosed
US-9708359-B2 Pyrrolopyrimidine nucleosides and analogs thereof CHIMERIX, INC. (US) 2017-07-18 — — US disclosed
US-9701706-B2 Pyrrolopyrimidine nucleosides and analogs thereof CHIMERIX, INC. (US) 2017-07-11 — — US disclosed
CN-104136498-B Novel liquid organopolysiloxanes and use thereof 道康宁东丽株式会社 2017-06-20 — — CN disclosed
US-20170137454-A1 PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL TRUSTEE 2017-05-18 — — US disclosed
US-20170044202-A1 PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL TRUSTEE 2017-02-16 — — US disclosed
US-20120032122-A1 METHOD FOR FORMING A CADMIUM CONTAINING NANOCRYSTAL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-02-09 — — US disclosed
US-20110233468-A1 PROCESS OF FORMING A CADMIUM AND SELENIUM CONTAINING NANOCRYSTALLINE COMPOSITE AND NANOCRYSTALLINE COMPOSITE OBTAINED THEREFROM AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-09-29 — — US disclosed
WO-2010062267-A1 METHOD OF FORMING A RARE EARTH METAL DOPED NANOPARTICLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-06-03 — — WO disclosed
WO-2010053572-A2 AMINOALCOHOL LIPIDOIDS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-05-14 — — WO disclosed
EP-2178790-A1 PROCESS OF FORMING A CADMIUM AND SELENIUM CONTAINING NANOCRYSTALLINE COMPOSITE AND NANOCRSTALLINE COMPOSITE OBTAINED THEREFROM Agency for Science, Technology and Research (SG) 2010-04-28 — — EP disclosed
WO-2009020430-A2 METHOD OF FORMING A CADMIUM CONTAINING NANOCRYSTAL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-02-12 — — WO disclosed
WO-2009020436-A1 PROCESS OF FORMING A CADMIUM AND SELENIUM CONTAINING NANOCRYSTALLINE COMPOSITE AND NANOCRSTALLINE COMPOSITE OBTAINED THEREFROM AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-02-12 — — WO disclosed
EP-0316618-A2 Multilayer flat light sensitive registration material BASF Aktiengesellschaft (DE) 1989-05-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137454-A1 PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF TYMP, PNP, DPYD HTT 3876/4885THRB 4398/4885MEN1 3288/4885
US-20170253628-A1 PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF TYMP, PNP, DPYD HTT 3876/4885THRB 4398/4885MEN1 3288/4885
US-20170044202-A1 PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF TYMP, ITPA, IMPDH1 HTT 3002/4885THRB 4124/4885MEN1 3416/4885
US-20230287029-A1 ANTIVIRAL PRODRUGS, PHARMACEUTICAL FORMULATIONS, AND METHODS MTAP, SARS1, RNGTT HTT 1997/4885THRB 3741/4885MEN1 3895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.