Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | NPR3 | P17342 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089179 | 0.80 | TDP1 (0.35) | TDP1ATMNPSR1POLBMEN1 | |
| SCHEMBL5548846 | 0.71 | CTSK (0.34) | CTSKCTSSNPR3NPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL27854513 | 0.71 | CTSK (0.41) | CTSKCTSSTDP1NPSR1POLB | |
| SCHEMBL3545331 | 0.69 | TDP1 (0.40) | TDP1ATMNPSR1POLBMEN1 | |
| SCHEMBL31039778 | 0.68 | TDP1 (0.36) | TDP1ATMNPSR1POLBMEN1 | |
| SCHEMBL27043289 | 0.66 | TDP1 (0.35) | TDP1NPSR1POLBMEN1KMT2A | |
| SCHEMBL9506355 | 0.65 | CTSK (0.50) | CTSKCTSSCA1CA2 | |
| SCHEMBL7365479 | 0.64 | CTSK (0.39) | CTSKCTSSTDP1MEN1KMT2A | |
| SCHEMBL27926587 | 0.64 | CTSK (0.39) | CTSKCTSSTDP1MEN1KMT2A | |
| SCHEMBL19411887 | 0.64 | TSHR (0.34) | POLBL3MBTL1MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799653-A2 | NOVEL HETEROCYCLES | Bayer Pharmaceuticals Corporation (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006023843-A2 | NOVEL HETEROCYCLES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |