SCHEMBL5548862

SCHEMBL5548862

NC(=O)Oc1ccncc1S

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.40
SIRT3 Q9NTG7 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA12 O43570 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
CA14 Q9ULX7 2/20 0.37
F7 P08709 1/20 0.36
F3 P13726 1/20 0.36
SARM1 Q6SZW1 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.36
SIRT6 Q8N6T7 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
SIRT5 Q9NXA8 1/20 0.36
SIRT4 Q9Y6E7 1/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM6B O15054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9572481 0.82 DYRK1A (0.43) DYRK1ASIRT3TDP1CA12CA2
SCHEMBL21581982 0.81 DYRK1A (0.40) DYRK1ASIRT3TDP1CA12CA2
SCHEMBL29256723 0.79 KDM4E (0.48) DYRK1ASIRT3TDP1CA12CA2
SCHEMBL21551047 0.78 DYRK1A (0.40) DYRK1ASIRT3TDP1CA12CA2
SCHEMBL21582000 0.78 SIRT3 (0.50) DYRK1ASIRT3TDP1CA12CA2
SCHEMBL29159564 0.78 CDK8 (0.47) DYRK1ASIRT3TDP1CA12CA2
SCHEMBL15880928 0.76 CA12 (0.49) DYRK1ASIRT3TDP1CA12CA2
SCHEMBL30600926 0.74 SIRT3 (0.55) DYRK1ASIRT3TDP1F7F3
SCHEMBL9413724 0.74 SIRT3 (0.55) DYRK1ASIRT3TDP1F7F3
SCHEMBL29134389 0.73 CA12 (0.53) DYRK1ACA12CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117693214-A Quantum dot light-emitting device, preparation method thereof and display device 广东聚华印刷显示技术有限公司 2024-03-12 CN claimed
CN-117693214-A Quantum dot light-emitting device, preparation method thereof and display device 广东聚华印刷显示技术有限公司 2024-03-12 CN disclosed
US-20070129371-A1 Novel ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-06-07 US disclosed
EP-1577302-A1 NOVEL ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
EP-0050261-B1 MOULDING MASSES STABILIZED AGAINST THERMOLYSIS WITH A LOW MONOMER CONTENT BAYER AG (DE) 1985-08-14 EP disclosed
EP-0050261-A1 Moulding masses stabilized against thermolysis with a low monomer content BAYER AG (DE) 1982-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129371-A1 Novel ethylenediamine derivatives C1R, C9, C1S DYRK1A 2209/4885SIRT3 291/4885TDP1 1949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.