SCHEMBL5549432

SCHEMBL5549432

CCCCCC[SiH](CCCCCC)[Zr](Cl)(Cl)(C1C(C)=Cc2ccccc21)C1C(C)=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.31
CNR2 P34972 3/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8679494 0.86
SCHEMBL1043690 0.86 ALDH1A1 (0.31)
SCHEMBL8678150 0.85
SCHEMBL8682025 0.84
SCHEMBL8679218 0.82
SCHEMBL5552430 0.81 SOAT1 (0.32)
SCHEMBL7907796 0.77 BCHE (0.30)
SCHEMBL6731701 0.76
SCHEMBL153452 0.75
SCHEMBL4877438 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2915824-A1 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Lummus Novolen Technology Gmbh (DE) 2015-09-09 EP disclosed
US-7285608-B2 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-10-23 US disclosed
EP-1740622-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Novolen Technology Holdings C.V. (NL) 2007-01-10 EP disclosed
WO-2005105863-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2005-11-10 WO disclosed
US-20050239979-A1 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2005-10-27 US disclosed