Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 6/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GALR2 | O43603 | 6/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553391 | 0.99 | GALR1 (0.42) | GALR1BCL6MAPTMEN1HTT | |
| Hydrochloric Acid SCHEMBL5549895 | 0.91 | GALR1 (0.42) | GALR1BCL6MAPTMEN1HTT | |
| SCHEMBL5553387 | 0.90 | GALR1 (0.42) | GALR1BCL6MAPTMEN1HTT | |
| Hydrochloric Acid SCHEMBL5555562 | 0.90 | GALR1 (0.38) | GALR1BCL6MAPTMEN1HTT | |
| SCHEMBL5554491 | 0.89 | GALR1 (0.39) | GALR1BCL6MAPTMEN1HTT | |
| SCHEMBL4838523 | 0.82 | GALR1 (0.48) | GALR1BCL6MAPTMEN1HTT | |
| Hydrochloric Acid SCHEMBL5555561 | 0.82 | GALR1 (0.38) | GALR1BCL6MAPTMEN1HTT | |
| Iodide SCHEMBL5553524 | 0.81 | GALR1 (0.47) | GALR1BCL6MAPTMEN1HTT | |
| SCHEMBL5554484 | 0.81 | GALR1 (0.39) | GALR1BCL6MAPTMEN1HTT | |
| Hydrochloric Acid SCHEMBL5549836 | 0.81 | GALR1 (0.44) | GALR1BCL6MAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268134-B2 | Medical devices employing triazine compounds and compositions thereof | REDDY US THERAPEUTICS, INC. (US) | 2007-09-11 | — | — | US | claimed |