SCHEMBL5550293

SCHEMBL5550293

CCC(CC)CCCOc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
LMNA P02545 2/20 0.42
MAPK10 P53779 1/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
MAPT P10636 6/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALOX15 P16050 2/20 0.39
ADORA3 P0DMS8 1/20 0.39
TSHR P16473 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
ADORA1 P30542 1/20 0.39
NPSR1 Q6W5P4 5/20 0.38
MAPK1 P28482 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163597 0.90 MAPT (0.44) GAALMNAMAPK10CNR1CNR2
SCHEMBL29357507 0.88 LMNA (0.41) GAALMNAMAPK10CNR1CNR2
SCHEMBL493631 0.88 LMNA (0.41) GAALMNAMAPK10CNR1CNR2
SCHEMBL5546836 0.87 TP53 (0.37) GAACNR1CNR2GPR55MAPT
SCHEMBL5584373 0.86 MAPT (0.49) GAALMNAMAPK10CNR1CNR2
SCHEMBL6057276 0.85 PTPN11 (0.48) GAALMNAMAPK10CNR1CNR2
SCHEMBL29378637 0.85 PTPN11 (0.48) GAALMNAMAPK10CNR1CNR2
SCHEMBL1467779 0.85 PTPN11 (0.48) GAALMNAMAPK10CNR1CNR2
SCHEMBL17920219 0.85 PTPN11 (0.48) GAALMNAMAPK10CNR1CNR2
SCHEMBL1290508 0.85 LMNA (0.42) GAALMNAMAPK10CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1808715-A2 Multilayered light diffuser plate Sumitomo Chemical Company, Limited (JP) 2007-07-18 EP disclosed
US-20070160828-A1 Multilayered light diffuser plate SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) 2007-07-12 US disclosed