Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.50 |
| ▸ | PPARA | Q07869 | 18/20 | 0.50 |
| ▸ | PPARD | Q03181 | 10/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556259 | 0.99 | PPARG (0.51) | PPARGPPARAPPARDACACB | |
| SCHEMBL5550981 | 0.89 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL6847766 | 0.88 | PPARA (0.48) | PPARGPPARAPPARD | |
| SCHEMBL14437953 | 0.87 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL4338050 | 0.85 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL5551032 | 0.85 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL4337259 | 0.84 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL5550989 | 0.84 | PPARA (0.55) | PPARGPPARAPPARD | |
| SCHEMBL5556283 | 0.84 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5550667 | 0.82 | PPARG (0.52) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20040116708-A1 | Insulin sensitizers; antidiabetic agents, antiinflammatory agents; inflammatory bowel disorders | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1375484-A1 | CARBOXYLIC ACIDS | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |