SCHEMBL6847766

SCHEMBL6847766

CCOC(Cc1ccnc(OCCOc2ccc(C3CCCCC3)cc2)c1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.48
PPARG P37231 17/20 0.48
PPARD Q03181 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5550981 0.99 PPARG (0.48) PPARAPPARGPPARD
SCHEMBL5556259 0.89 PPARG (0.51) PPARAPPARGPPARD
SCHEMBL5550663 0.88 PPARG (0.50) PPARAPPARGPPARD
SCHEMBL4332364 0.85 PPARG (0.53) PPARAPPARGPPARD
SCHEMBL4335092 0.84 PPARG (0.54) PPARAPPARGPPARD
SCHEMBL5554541 0.84 PPARA (0.61) PPARAPPARGPPARD
SCHEMBL5550680 0.83 PPARA (0.56) PPARAPPARGPPARD
SCHEMBL5555664 0.82 PPARA (0.53) PPARAPPARGPPARD
SCHEMBL5550678 0.81 PPARA (0.53) PPARAPPARGPPARD
SCHEMBL5554502 0.81 PPARA (0.53) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7253178-B2 Carboxylic acids EISAI CO., LTD. (JP) 2007-08-07 US disclosed
US-7253178-B2 Carboxylic acids EISAI CO., LTD. (JP) 2007-08-07 US disclosed
EP-1375484-A1 CARBOXYLIC ACIDS Eisai Co., Ltd. (JP) 2004-01-02 EP disclosed