Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.52 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 2/20 | 0.48 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837794 | 0.85 | NR4A2 (0.58) | KDM5BKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL30822604 | 0.82 | GLRA1 (0.51) | HPGDLMNAKDM5BKDM4CKDM5A | |
| SCHEMBL27189260 | 0.82 | GLRA1 (0.51) | HPGDLMNAKDM5BKDM4CKDM5A | |
| SCHEMBL13876023 | 0.82 | MAOB (0.46) | HPGDLMNAKDM5BKDM4EKDM4C | |
| SCHEMBL15778481 | 0.81 | KDM5A (0.57) | HPGDLMNAKDM5BKDM4EKDM6B | |
| SCHEMBL31562679 | 0.81 | PPIA (0.50) | HPGDLMNAKDM5BKDM4EKDM6B | |
| SCHEMBL29173821 | 0.80 | KDM4E (0.55) | HPGDKDM5BKDM4EKDM6BKDM5C | |
| SCHEMBL30931811 | 0.80 | LMNA (0.59) | HPGDLMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL730969 | 0.80 | LMNA (0.59) | HPGDLMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL24646021 | 0.79 | ACACB (0.44) | HPGDLMNAKDM5BKDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20040116708-A1 | Insulin sensitizers; antidiabetic agents, antiinflammatory agents; inflammatory bowel disorders | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1375484-A1 | CARBOXYLIC ACIDS | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |