Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119300 | 0.85 | ALDH1A1 (0.54) | HPGDGAAMAPK1KIF11ALDH1A1 | |
| SCHEMBL1530134 | 0.82 | CA12 (0.52) | HPGDGAAMAPK1KIF11ALDH1A1 | |
| SCHEMBL9390760 | 0.82 | HPGD (0.58) | HPGDGAAMAPK1KIF11ALDH1A1 | |
| SCHEMBL11472225 | 0.81 | CYP3A4 (0.56) | HPGDGAAMAPK1ALDH1A1CA12 | |
| SCHEMBL3781788 | 0.79 | HPGD (0.55) | HPGDGAAMAPK1KIF11ALDH1A1 | |
| SCHEMBL11239737 | 0.79 | GAA (0.59) | HPGDGAAMAPK1KIF11CA2 | |
| SCHEMBL1542334 | 0.79 | ALDH1A1 (0.49) | HPGDKIF11ALDH1A1CA12CA1 | |
| SCHEMBL12764248 | 0.79 | CA1 (0.47) | HPGDGAAMAPK1KIF11ALDH1A1 | |
| SCHEMBL1530252 | 0.78 | HPGD (0.58) | HPGDGAAMAPK1KIF11ALDH1A1 | |
| SCHEMBL526634 | 0.78 | HPGD (0.54) | HPGDGAAMAPK1KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491023-B1 | COUMARIN COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN INC (US) | 2014-12-31 | — | — | EP | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-0458746-A1 | Azo dyes, process for their preparation and the use thereof | CIBA-GEIGY AG (CH) | 1991-11-27 | — | — | EP | disclosed |