Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 15/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873929 | 0.93 | AOC3 (0.54) | AOC3RORC | |
| SCHEMBL4875894 | 0.93 | AOC3 (0.61) | AOC3RORCHTT | |
| SCHEMBL5545300 | 0.92 | AOC3 (0.62) | AOC3RORCHTT | |
| SCHEMBL4988925 | 0.90 | AOC3 (0.59) | AOC3MAPT | |
| SCHEMBL4987464 | 0.88 | AOC3 (0.59) | AOC3NPSR1HTTMAPT | |
| SCHEMBL4866130 | 0.87 | AOC3 (0.48) | AOC3 | |
| SCHEMBL4991572 | 0.87 | AOC3 (0.49) | AOC3SMN1; SMN2 | |
| SCHEMBL4982477 | 0.87 | AOC3 (0.49) | AOC3SMN1; SMN2 | |
| SCHEMBL4873656 | 0.86 | AOC3 (0.63) | AOC3MAPT | |
| SCHEMBL3937291 | 0.86 | AOC3 (0.67) | AOC3SMN1; SMN2NPSR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | ASTELLAS PHARMA INC. (JP) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | VCAM1, VAPB, VAPA | AOC3 386/4885SMN1; SMN2 1527/4885NPSR1 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.