Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18525626 | 0.82 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL14000911 | 0.82 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL11985625 | 0.79 | TSHR (0.40) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL16587991 | 0.79 | TSHR (0.40) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL7028944 | 0.78 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL7023744 | 0.77 | TSHR (0.50) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL19829244 | 0.76 | CETP (0.41) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL29128959 | 0.76 | TSHR (0.40) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL21327698 | 0.75 | TSHR (0.48) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL8711753 | 0.75 | TSHR (0.36) | TSHRIDO1TP53AGXTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1827501-A2 | STABILIZED POLYMERIC THIOL REAGENTS | Nektar Therapeutics Al, Corporation (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006069388-A2 | STABILIZED POLYMERIC THIOL REAGENTS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2006-06-29 | — | — | WO | disclosed |