SCHEMBL8711753

SCHEMBL8711753

C=CC(Br)(CCC)OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
IDO1 P14902 1/20 0.34
CA1 P00915 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
AGXT P21549 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CETP P11597 3/20 0.33
MAPK1 P28482 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 1/20 0.33
CYP3A4 P08684 1/20 0.32
LMNA P02545 1/20 0.32
MBOAT4 Q96T53 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6811521 0.89 CETP (0.39) TSHRALDH1A1TP53CETPMAPK1
SCHEMBL8709144 0.88 CETP (0.41) TP53CETPMAPK1MBOAT4
SCHEMBL28762265 0.76 CETP (0.33) TSHRIDO1CA1ALDH1A1TP53
SCHEMBL5551877 0.75 TSHR (0.41) TSHRIDO1ALDH1A1TP53AGXT
SCHEMBL8711127 0.75 TSHR (0.41) TSHRIDO1CA1ALDH1A1AGXT
SCHEMBL16177914 0.74 ATM (0.37) TSHRIDO1ALDH1A1AGXTTDP1
SCHEMBL11985625 0.74 TSHR (0.40) TSHRIDO1ALDH1A1TP53AGXT
SCHEMBL8707828 0.73 CETP (0.39) TSHRALDH1A1TP53CETPMAPK1
SCHEMBL9025083 0.73 TSHR (0.43) TSHRIDO1CA1ALDH1A1TP53
SCHEMBL18525626 0.73 TSHR (0.43) TSHRIDO1ALDH1A1TP53AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5731395-A POLYMER CONTAINING DIVINYLBENZENE AND STYRENE COMPOUND ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed